No Trainers

This place is looking like a ghost town

Imagine a world where you are the only Pokemon trainer (except for Gym Leaders and the odd Team Rocket member). Every town looks like a ghost town (even Lavender Town).

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Just to spice things up a bit more - imagine if you couldn't run from ANY wild Pokemon, meaning your (likely under levelled) team is in a lot of danger. Oh, and why not make it a Nuzlocke too - just for old times sake.